A gut microbiome test is a screening tool used to analyse the composition and diversity of microorganisms in your digestive system.
The gut microbiome consists of trillions of bacteria, viruses, and fungi that live in the digestive tract. It plays a key role in almost every aspect of human health.
The gut microbiome is a vital community of microorganisms that resides within the human digestive system. This ecosystem plays an essential role in human health, influencing digestion, metabolism, immune system function, and even mood regulation through the gut-brain axis. A balanced gut microbiome promotes optimal digestion, assists in nutrient absorption, and helps defend against harmful pathogens, while an imbalance has been linked to various conditions, including obesity, diabetes, inflammatory bowel disease, and mental health disorders.
A number of gut bacteria (e.g, Lactobacilli, E. coli, Bifidobacterium, Streptococcus thermophilus) contribute to maintenance of human health state, whereas others (e.g., Clostridium difficile, Campylobacter, Enterococcus faecalis, Helicobacter pylori) are more prevalent in disease states.
The human gut microbiome begins to form at birth and undergoes significant changes during early life, ultimately stabilizing around the age of three. Important bacterial genera present in a healthy gut include Bacillus, Lactobacillus, and Enterococcus. The ratio of Firmicutes to Bacteroidetes in the gut microbiome can impact weight, as higher levels of Firmicutes are associated with obesity. The gut microbiome serves various functions, including assisting in the digestion of food, absorbing nutrients like vitamins and minerals, and detoxifying harmful foreign substances. The gut plays a vital role in interacting with the external environment, with millions of microbial genes supporting essential bodily functions. The gut epithelium, with a surface area of around 300 m2 in adults, acts as a barrier to prevent harmful bacteria from entering the bloodstream and causing inflammation. The gut microbiome also contributes to maintaining the immune system, particularly through the production of immunoglobulin A antibodies that help protect against pathogens by promoting colonization resistance.
Testing the gut microbiome provides valuable insights that can guide both personal health management and clinical decision-making. The composition of the gut microbiome has been shown to influence various aspects of health, from digestion and metabolism to immune function and mood. Identifying the specific bacteria and other microbes present, as well as their relative balance, can help uncover potential causes of digestive issues, such as bloating, irritable bowel syndrome, inflammatory skin disorders and food intolerances, which are often linked to microbial imbalances.
Furthermore, microbiome testing can reveal markers of inflammation and gut barrier function, which are increasingly recognized as critical factors in chronic conditions like autoimmune diseases, metabolic disorders, and mental health issues. By understanding an individual’s unique microbial profile, healthcare providers can tailor dietary, probiotic, and lifestyle recommendations to improve gut health, enhance nutrient absorption, and support overall wellness. For those seeking preventive care, microbiome testing offers an evidence-based approach to fostering a balanced gut environment that aligns with long-term health goals.
An imbalance and changes in the gut microbiome can contribute to various skin disorders due to the influence of specific metabolic byproducts on physiological processes. Factors such as environmental determinants, host factors like pancreatic enzymes and bacterial factors such as microbial enzymes, can all impact the composition of the gut microbiota. Dysbiosis in the gut, characterized by biomarkers like free phenol and p-cresol, can lead to common skin issues like psoriasis, atopic eczema, and acne. Less common but severe conditions such as rosacea, alopecia areata, and hidradenitis suppurativa may also be associated with gut dysbiosis. Clinical trials and studies suggest that modulation of the gut microbiome may even influence susceptibility to allergic diseases and asthma.
Gut microbiome testing allows individuals to gain valuable insights into the unique microbial composition within their digestive tract, offering a personalized approach to understanding health and identifying potential imbalances. By analyzing the diversity and types of bacteria, fungi, and other microbes present, these tests can uncover underlying causes of digestive issues, nutrient deficiencies, and even chronic inflammation.
Incorporating gut microbiome testing into healthcare can support tailored nutritional and lifestyle recommendations that may improve health outcomes, guide therapeutic interventions, and support preventive health strategies.
A gut microbiome test typically involves collecting a small stool sample, which is then analyzed to identify the types and amounts of microorganisms in the digestive tract. Here’s an overview of how the process works:
Sample Collection: The individual is provided with a sterile collection kit that includes detailed instructions on how to collect the stool sample at home. The kit usually includes a sterile container, and a preservative solution to ensure that the sample remains viable during transit.
Sample Preservation and Shipping: Once collected, the sample is preserved according to the instructions—often in a small vial containing a stabilizing solution—and then sealed. It is then mailed back to the lab for analysis.
Laboratory Analysis: In the lab, the sample undergoes DNA sequencing. This technology allows scientists to identify specific microbial strains and determine their relative abundance in the sample.
Data Interpretation and Report Generation: Once analyzed, the lab compiles a report detailing the microbial diversity within the sample, including which types of bacteria, fungi, and other microbes are present. The report may also include interpretations of how these microbes are associated with specific health conditions or dietary needs, along with recommendations for diet and lifestyle changes to improve gut health.
Results and Recommendations: Results are either shared directly with the individual or through a healthcare provider. Based on the findings, targeted recommendations may include dietary adjustments, probiotics, or lifestyle changes to encourage a healthy microbial balance.
Gut microbiome testing offers a detailed look into the digestive ecosystem and can provide personalized insights to support health and wellness goals.
It tests for the diversity and ratio of strains that account for your unique gut microbiome. Certain strains are linked to inflammation, obesity, Alzheimer's, metabolism and cancer risk.
Common gut microbiome strains:
The complex communication between gut and brain is intimately connected. The report measures the abundance of bacterial groups associated with neurotransmitters and essential amino acids.
Numerous metabolites and enzymes are produced by the gut microbiome to support our general well-being and to promote health.
Food that is digested is chiefly through the action of the gut microbiome. The ability to digest, breakdown food for energy production is an essential ability of our gut microbiome.
It measures:
A graphical representation is given is show the likelihood of certain diseases based on your gut microbiome composition and results.
Prebiotics, probiotics, and postbiotics all play distinct roles in gut health and overall well-being:
Your gut microbiome screening test is sent to an ISO-certified healthcare organisation, AMILI, that is registered in Singapore. It is southeast asia's first and only precision gut microbiome company that is backed by the world’s largest multi-ethnic, Asia-centric gut microbiome database and biobank. It is supported by a panel of clinicians, scientists and advisors with expertise in microbiome science.
| TREATMENT | PRICE (SGD)* |
|---|---|
| Consultation | from 39.9 |
| Gut Microbiome Test | 399 |
While microbiome screening can give valuable insights, the field is still evolving. Different labs and methods can yield slightly different results, and individual microbiome profiles can vary over time. It’s best to use the results as a guide rather than a definitive diagnosis.
Your results can guide dietary and lifestyle adjustments, like increasing fiber intake, avoiding certain foods, or taking probiotics. Many screenings include personalized recommendations, and some people opt to consult with a healthcare provider to interpret their results further.
There are no risks associated with gut microbiome testing since it is non-invasive
For general health monitoring, once or twice a year is sufficient. People with specific health goals or conditions might test more frequently to track changes and monitor progress.
The gut microbiome screen is $399. Please note that this is not inclusive of a medical consultation.
No, a microbiome test alone cannot diagnose diseases. It can indicate imbalances that might be associated with certain conditions, but further medical evaluation is needed for diagnosis.
It typically takes 3-4 weeks to receive results. Your doctor will discuss the findings with you when the results are out.
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