oral finasteride hair loss treatment

Oral finasteride hair loss treatment

Clinically proven treatment for male patttern hair loss or androgenetic alopecia.

Stop hair loss, regrow hair and renew your confidence with FDA-approved oral finasteride hair loss treatment.

Male pattern hair loss (Androgenetic Alopecia)

What is oral finasteride?

Oral finasteride is a FDA-approved treatment for male pattern hair loss or androgenetic alopecia. Since the inception of oral finasteride hair loss treatment in 1997, it has helped many individuals halt relentless hair loss and improve hair growth.

how does oral finasteride work?

One of the reasons for male pattern hair loss is the effect of dihydrotestosterone (DHT) on the hair follicles. Other reasons include genetics, compromised vascular supply around the hair follicle and reduced anagen phase. Testosterone in the body is converted to DHT by the enzyme 5-alpha-reductase. Oral finasteride works by inhibiting the action of the enzyme 5-alpha-reductase and therefore reduces the circulating levels of DHT and its effects on the hair follicle. 

dihydrotestosterone finasteride
Loss of hair at back of scalp

how effective is oral finasteride hair loss treatment?

Studies have shown oral finasteride 1mg/day to be effective in treating patients with androgenetic alopeica and long-term use of up to 5 years has shown significant hair growth and permanent stabilization of hair loss. A Japanese study of over 3000 males with hair loss demonstrated that 11.1% of subjects exhibited significant hair regrowth with finasteride use, 36.5% exhibited moderate growth, and 39.5% had only a slight increase in hair growth over a period of 3 years

how safe is oral finasteride?

Oral finasteride is a well-studied treatment for male pattern hair loss over more than 2 decades. Most patients tolerate the treatment well. In clinical trials, about 1.4% of patients had to stop the treatment due to side effects. The risk of loss of libido, erectile dysfunction and reduced ejaculate volume is less than 2%, and these symptoms usually improves over time. 

Older men should have regular checks of their prostate with a serum prostate specific antigen (PSA) test and digital rectal examination. There is an increased risk of high-grade prostate cancer due to masking of PSA levels and delayed detection.

Sustained and improve hair density

who can take oral finasteride?

Oral finasteride is FDA-approved for male pattern hair loss or androgenetic alopecia in men only.

Who is unsuitable for it?

It is not approved for use in women when they are or are potentially pregnant and is assigned to pregnancy category X due to risk of causing ambiguous genitalia in a male fetus.

Which area of the scalp can i see improvement?

Long term treatment of oral finasteride for hair loss has been shown to decrease the likelihood of further hair loss in men. The drug is more effective at the vertex region compared to the frontal scalp.

what about dutasteride for hair loss?

Dutasteride, in particular, is noteworthy as it is approximately 3 times more potent against type II 5 alpha-reductase enzyme and 100 times more potent against the type 1 enzyme. It is often used for patients who have not experienced satisfactory results with finasteride. The adverse effect profile of dutasteride is similar to that of finasteride.

Frequently Asked Questions On Oral Finasteride

Oral finasteride 1mg is a 5 alpha reductase inhibitor and works by reducing the amount of active androgen, dihydrotestesterone (DHT) in men. More than 90% of men on this oral medication will experience a slowing of hair loss, and up to 60% may experience hair regrowth. These results are sustained over 5 years in one study, and is generally well tolerated. Hair regrowth with treatment is more prominent over the midscalp and vertex areas

Oral finasteride is contraindicated in women of childbearing age, pregnant women and children. Studies have shown that it causes male foetal genital abnormalities during pregnancy.

  • About 2-4% of patients may experience a loss of libido, erectile dysfunction and reduced ejaculatory volume. However, there are studies to suggest that the rates of sexual dysfunction reduces over time whilst on treatment.
  • Gynaecomastia (breast enlargement in men)
  • Orthostatic hypotension. The sensation of feeling giddy when you stand up due to low blood pressure. The risk is increased when you are on blood pressure medicines such as alpha-blockers.
  • Possibly slight increased risk of anxiety, depression and suicide ideation.
  • Uncommonly, some patients may experience dizziness, weakness, shortness of breath and a skin rash.
  • Post-finasteride syndrome is a constellation of side effects that persists after discontinuation of therapy. This is controversial and is currently being studied.

It is recommended that oral finasteride be continued indefinitely in order to salvage the hair preserved by the initial treatment. There are cases of rapid hair loss upon stopping oral finasteride therapy, and all gains made will be lost within 12 months.

A systematic review and meta-analysis in 2020 suggest an improvement in hair density and global photographic evaluation scores of combined topical minoxidil and oral finasteride compared to monotherapy. In addition, side effects of combination treatment did not differ much from that of standalone treatment.

Generally, there is very little data to support that low dose oral finasteride causes infertility. Studies have shown that even in cases of infertility, it is reversible upon stopping treatment.

No, blood donation is no allowed and is contraindicated for those while on treatment and 6 months after your last dose of oral finasteride treatment.

A 4-week course of treatment is $64.9 before GST.

Topical Minoxidil has an interesting story. It was discovered by accident, as doctors were using the oral form to treat high blood pressure and noticed the incidental side effect of increased hair growth. While it is unknown how minoxidil actually works, it should be used for at least 6 months for maximum efficiency. It is common for hair to shed for the first 2-6 weeks when starting treatment, but treatment should be continued as it will slow progression of the hair loss and partially restore hair in some cases over time. Minoxidil treatment can be used for male and female pattern hair loss.

schedule a consultation for oral finasteride hair loss treatment in singapore

To receive the best male or female hair loss treatment results, Dr.Ng offers a personalised treatment plan that is unique to your condition. Contact us to schedule an appointment with Dr.Ng today.

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References:
  1. Sato A, Takeda A. Evaluation of efficacy and safety of finasteride 1 mg in 3177 Japanese men with androgenetic alopecia. The Journal of dermatology. 2012 Jan;39(1):27-32.
  2. Nestor MS, Ablon G, Gade A, Han H, Fischer DL. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics. Journal of cosmetic dermatology. 2021 Dec;20(12):3759-81.
  3. Chen L, Zhang J, Wang L, Wang H, Chen B. The efficacy and safety of finasteride combined with topical minoxidil for androgenetic alopecia: a systematic review and meta-analysis. Aesthetic Plastic Surgery. 2020 Jun;44:962-70.