rejuran s acne scars singapore

What is Rejuran S for Acne Scars?

Rejuran S for acne scars treatment uses high viscosity long chain polynucleotide (PN). Polynucleotide provides a structural scaffold to induce wound repair, collagen remodelling and has anti-inflammatory effects.

Rejuran S is Korean FDA-approved and Singapore HSA-approved for medical use

How is Rejuran S Different from Rejuran Healer?

Rejuran S
Rejuran Healer

Rejuran Healer has the active ingredient polynucleotide of medium viscosity. The primary purpose is for an overall improvement in skin elasticity, hydration and revitalisation. Rejuran Healer exerts it regenerative effects by stimulating more fibroblasts. Fibroblasts are important skin cells that have the ability to regenerate the building blocks of healthy skin;  Collagen, Elastin and Glyscoaminoglycans. Rejuran Healer comes in 2mls syringe which is sufficient for a full face treatment.

Rejuran S is more viscous (concentrated) compared to Rejuran Healer. It provides a structural support to enhance collagen remodelling and improved skin elasticity. After injection of the polynucleotide, collagen fibers are denser due to an increase in fibroblasts (cells that produce collagen). Rejuran S comes in a 1ml syringe. It is used to improve the appearance of acne scars and depressed scars following surgery and trauma. Rejuran S treatment is often used as to assist the primary treatment, which for example could be, INFINI fractional resurfacing or subcision. Rejuran S is considered an adjunctive treatment rather than a primary one in itself.

How is Rejuran S Procedure Done?

After a clinical assessment, your skin is cleansed and numbing cream is applied. Small amounts of Rejuran S is introduced at the base of the scar with a fine 30G needle. A topical antibiotic may be prescribed to prevent infections.

Any Downtime with Rejuran S Acne Scars Treatment?

There may be mild transient redness, swelling and itchiness following the procedure. Needle marks will fade within 2-3 days. Bruising, if any, may resolve by itself in about 7-10 days. You can resume normal activities in a few days and makeup can usually be used the next day.

How many Rejuran S Treatments Will I Need?

On average, we recommend 3-4 Rejuran S treatments spaced about 4-6 week intervals. 

Is Rejuran S Suitable for All Scar Types?

Scars differ in their morphologic subtypes (rolling, boxcar, ice-pick), depth and maturity. We usually recommend treating deeper scars first before tackling more superficial scars. 

By itself, Rejuran S will not improve deep rolling and ice pick scars. These are treated with subcision and TCA CROSS respectively. Rejuran S treatment is useful to assist the primary treatment method instead of being used as monotherapy for deeper scar types.

How Much Is the Rejuran S Treatment?

Rejuran S treatment is priced at $500 per 1ml syringe.


  1. Kim JH, Jeong JJ, Lee YI, Lee WJ, Lee C, Chung WY, et al. Preventive effect of polynucleotide on post-thyroidectomy scars: a randomized, double-blinded, controlled trial. Lasers Surg Med 2018;50:755-62.
  2. Rho NK. Chung ST. Treatment of a Full-thickness Laceration Scar on the Forehead Using a 1,064-nm Fractional Picosecond Laser and Polynucleotide Gel Injection. Med Laser 2018;7(2):88-90
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