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Cystic Acne 

cystic acne treatment clinic in Singapore
Table of Contents

What is cystic acne?

Cystic acne is a severe form of acne characterised by deep, inflamed cysts or nodules beneath the skin’s surface. Unlike ordinary pimples, these cysts develop from blocked pores and bacterial infection that trigger intense inflammation. They are often painful to touch, can last for weeks or months, and have a high risk of leaving permanent scars if not treated properly. Because cystic acne penetrates deeper into the skin, it requires timely medical attention to prevent complications and preserve skin health.

Cystic Acne Singapore
Cystic acne is a severe form of acne that develops deep beneath the skin, causing painful, inflamed lumps that often lead to scarring if left untreated.

What causes cystic acne?

Cystic acne develops when hair follicles become clogged with oil, dead skin cells, and bacteria, leading to a deep infection under the skin. Several factors can increase the likelihood of developing this condition:

  • Geneticsa family history of severe acne can increase the risk, as inherited skin traits may cause glands to produce more oil or respond strongly to hormonal changes [1].
  • Skin and oil production – naturally oily skin or overactive sebaceous glands make pores more prone to blockage.
Cause of Cystic Acne Singapore
Acne forms when pores become blocked by excess oil and dead skin cells, leading to bacterial growth, inflammation, and the development of pimples or cysts.

Cystic acne can present as large, painful lumps most commonly on the face, jawline, chest, back, or shoulders. These lesions can range from small microcysts to large nodules several centimetres in size, making early treatment important to relieve pain, minimise scarring, and restore skin confidence.

How is cystic acne different from milder acne?

Cystic acne develops much deeper in the skin compared to milder forms of acne, which is why over-the-counter products, medicated creams, and superficial treatments like chemical peels are often ineffective. Because the inflammation occurs in the lower layers of the skin, cystic acne is usually more painful, lasts longer, and carries a much higher risk of permanent scarring if left untreated.

Unlike whiteheads or blackheads that may resolve quickly, cystic acne lesions are not “poppable.” They tend to cause significant swelling, tenderness, and emotional distress due to their severity and visibility. 

Recognising the difference between cystic acne and milder types of acne is important, as early medical treatment can reduce pain, limit scarring, and prevent long-term damage to the skin.

TypeAcne CystAcne NodulePapules/PustulesComedones
DescriptionDeep, painful, pus-filled lesionsLarge, solid, painful lumpsSmall raised red or pus-filled bumpsBlackheads or skin-coloured bumps
InflammationHighHighModerateMinimal/none
ScarringHighHighModerateMinimal
Size>0.5 cm>1 cmSmallSmall
PainSignificantSignificantMild to moderateNone

Because of its severity, cystic acne should not be managed with home remedies alone. Specialist treatment is essential to control inflammation, protect the skin, and minimise permanent scarring.

How can I tell if I have cystic acne?

Cystic acne is a severe form of inflammatory acne that presents as painful, swollen bumps under the skin. These lesions appear red, feel tender to touch, and may release pus when they rupture. Unlike common pimples that form closer to the skin’s surface, cystic acne develops deeper within the dermal layers, making it more persistent and more likely to scar.

The key distinction between cystic acne and nodular acne is the presence of pus. Nodular acne is deeply embedded, hard, and painful but does not typically produce pus. In contrast, cystic acne often leads to inflamed pus-filled lesions. Some individuals also develop nodulocystic acne, which is a combination of both nodular and cystic acne.

Features that suggest cystic or nodulocystic acne include:

  • Depth – lesions form deep within the skin, unlike milder acne which is more superficial.
  • Size – bumps are usually larger than 1 cm and can persist for long periods.
  • Location – commonly found on the cheeks and jawline, but can also appear on the back, chest, and sometimes near the ears or hairline.
  • Tenderness – lesions are painful, may affect daily activities, and can disturb sleep.
  • Duration – they often last for weeks to months, with a tendency to flare up repeatedly in a chronic, relapsing-remitting pattern.

Because cystic acne can cause scarring and emotional distress, recognising these features early and seeking specialist care is crucial for effective management.

What causes nodulo-cystic acne?

Nodulo-cystic acne forms when multiple factors combine to trigger deep inflammation within the skin. These include excess oil, clogged pores, bacterial activity, and an exaggerated immune response.

Key causes include:

  • Bacterial overgrowth – Cutibacterium acnes bacteria (C. acnes) multiply inside blocked follicles, worsening the infection.
  • Chronic inflammation – the body’s immune reaction penetrates deeper layers of the skin, leading to painful nodules and cysts.
  • Dermal damage – persistent inflammation disrupts collagen and elastin fibres, which support the skin, resulting in acne scars or keloid formation.

Because nodulo-cystic acne develops so deeply within the dermis, it is more severe than common acne and requires timely medical treatment to reduce the risk of permanent scarring.

What can I do to avoid cystic acne?

While cystic acne cannot always be fully prevented, adopting the right skin care habits and lifestyle choices can reduce flare-ups and lower the risk of scarring. Early treatment is also important to keep the condition under control.

Tips to help minimise cystic acne include:

  • Choose non-comedogenic products – avoid oils such as isopropyl myristate and lanolin that can clog pores.
  • Avoid harsh scrubbing – over-exfoliating can irritate the skin and worsen inflammation.
  • Use cosmetics with care – limit products that contain pore-clogging ingredients like mica and certain dyes.
  • Be cautious with eye creams – these are often thicker in texture and can block pores if overused.
  • Cleanse after sweating – wash your face after exercise to remove sweat and bacteria that can trigger breakouts.
  • Avoid heavy balms and wax-based lip products – petroleum and wax-based formulas may cause acne around the mouth.
  • Opt for fragrance-free skincare – added fragrance can irritate sensitive or acne-prone skin.
  • Watch your diet – cut back on high-glycaemic foods (white bread, biscuits, glutinous rice) and dairy, which may worsen acne in some individuals.

Maintaining a gentle skincare routine and making mindful product choices can make a noticeable difference. For persistent or severe acne, medical treatment is essential to prevent long-term damage.

How to Prevent Cystic Acne Singapore
To prevent cystic acne, you must follow a daily skincare routine that includes gentle cleansing, non-comedogenic products, and avoiding harsh scrubbing or irritating ingredients.

Personalised Acne Care

Managing acne effectively requires a tailored approach, as no two patients experience the condition in the same way. At our clinic, we design acne treatment plans that are practical, sustainable, and suited to your lifestyle. This not only improves treatment success but also helps prevent relapses and long-term scarring.

Factors we consider when customising your acne care include:

  • Severity of acne – from mild to severe cystic breakouts.
  • Location of acne – whether it affects the face, jawline, chest, or back.
  • Presence of scarring – existing acne scars or high risk of future scarring.
  • Skin type – darker skin tones are more prone to post-inflammatory hyperpigmentation.
  • Family history – a genetic predisposition may influence acne severity and duration.
  • Duration of acne – how long the condition has been present.
  • Response to past treatments – effectiveness and tolerance of previous therapies.

By considering these factors, we create a treatment plan that is personalised, effective, and focused on achieving clearer, healthier skin over the long term.

What treatment options are available for acne cyst?

Treatment for cystic acne depends on the severity of the condition, medical history, skin type, and individual response. Both procedural and medical treatments are available to reduce inflammation, relieve pain, and prevent long-term scarring.

Procedural Treatments

  • Cyst drainage – when pus-filled cysts cause significant discomfort, minor drainage may be required [7]. Performed under local anaesthesia, this procedure provides immediate relief and usually heals well with minimal scarring.

Medical Treatments

  • Topical retinoidsprescription-only topical retinoids help unclog pores, reduce inflammation, and improve pigmentation [8]. They are stronger and more effective than over-the-counter retinol creams.
  • Oral antibiotics – oral antibiotics target C. acnes bacteria and reduce deep skin inflammation. They are often prescribed alongside topical therapies for better results. However, prolonged use can lead to antibiotic resistance, so they are carefully monitored.
  • Oral retinoids (Isotretinoin) oral isotretinoin, derived from Vitamin A, is considered the most effective treatment for severe or nodulocystic acne [9]. Studies show more than 95% of patients improve after a full treatment course [10]. By reducing oil production and shrinking sebaceous glands, isotretinoin offers long-term control. Suitability, dosage, and side effects are thoroughly discussed before treatment begins.

With timely treatment, cystic acne can be managed effectively, reducing pain and minimising the risk of permanent scarring.                                                                     

Treatment for Cystic Acne Singapore
Treatment for cystic acne may include prescription oral medications such as antibiotics or isotretinoin, used under medical supervision for severe cases.

How Dr. Ng treats cystic acne?

With more than 15 years of clinical experience, Dr. Ng understands the significant physical and emotional impact cystic acne can have on patients. Acne affects both men and women across all age groups and can persist for months or even years without proper treatment.

Dr. Ng adopts a patient-centred approach that combines scientific evidence with his extensive clinical expertise. Each treatment plan is carefully tailored to the individual’s skin type, acne severity, and lifestyle, as it helps ensure the best possible outcomes. By addressing both active breakouts and the risk of future scarring, Dr. Ng focuses on restoring clear, healthy skin and improving long-term confidence.

Early intervention is key. Seeking timely treatment with Dr. Ng can help prevent permanent scarring, reduce relapses, and support lasting improvements in skin health.

Cystic Acne Treatment Price in Singapore

At APAX Medical, the cost of cystic acne treatment varies depending on the type of therapy, the severity of the condition, and the individual needs of each patient. We provide transparent pricing so you know what to expect before starting your treatment plan. Below are the starting prices for common cystic acne treatments:

TreatmentPrice
Oral Antibioticsfrom $30
Topical Retinoidfrom $40
Oral Isotretinoinfrom $80
Injection Steroidsfrom $120
Drainage of Cystfrom $150
Laser Acne Treatmentfrom $399

Summary 

Cystic acne is a severe form of acne that develops deep within the skin, causing painful, swollen lesions that often persist for weeks or months. Unlike milder acne, it carries a high risk of scarring and typically does not respond to over-the-counter treatments. Factors such as genetics, hormonal changes, lifestyle, and bacterial overgrowth can all contribute to its development. Recognising cystic acne early is important, as it differs from nodules, pustules, and comedones in severity, pain, and long-term effects.

Management involves a personalised approach that may include skincare adjustments, lifestyle modifications, and medical treatments. Options range from intralesional injections and cyst drainage to prescription therapies such as topical retinoids, oral antibiotics, and oral isotretinoin. With professional care, most patients achieve significant improvement, reduced recurrence, and prevention of permanent scarring.

If you are struggling with persistent, painful acne or are concerned about scarring, schedule a consultation with APAX Medical for in-depth diagnosis, personalised care, and effective treatment tailored to your skin needs.

Frequently Asked Questions (FAQs) 

What causes cystic acne?

It is caused by a combination of excess oil production, clogged pores, bacterial overgrowth, hormonal changes, and an exaggerated inflammatory response.

Is cystic acne the same as nodular acne?

No. Nodular acne consists of deep, hard, painful lumps without pus, while cystic acne usually contains pus and is more inflamed.

Who is more likely to get cystic acne?

Teenagers, young adults, people with a family history of severe acne, those with oily skin, and individuals with hormonal imbalances are more at risk.

Can diet affect cystic acne?

While diet is not the sole cause, high-glycaemic foods (sugary snacks, white bread, glutinous rice) and dairy may trigger or worsen breakouts in some individuals.

Does stress cause cystic acne?

Stress does not directly cause acne, but it can worsen inflammation and hormonal fluctuations, increasing the risk of flare-ups.

Can cystic acne go away on its own?

Milder cases may improve, but severe cystic acne often persists and can cause permanent scarring without medical treatment.

Can cystic acne cause scarring?

Yes. Because it forms deep within the skin, cystic acne frequently leads to pitted scars, dark marks, or even keloids if not treated early.

What is the best treatment for cystic acne?

Treatment varies but may include intralesional steroid injections, topical retinoids, oral antibiotics, oral isotretinoin, drainage of cysts, or laser therapy.

Are oral isotretinoin treatments safe?

Yes, but they are only prescribed under strict medical supervision due to potential side effects. Most patients see more than 90% improvement after treatment.

Can I use over-the-counter creams for cystic acne?

No. OTC creams and face washes are usually ineffective for cystic acne, as the inflammation occurs deep in the dermis.

How long does cystic acne treatment take?

Treatment duration depends on severity, but significant improvement is often seen within a few weeks to months with consistent therapy.

Can cystic acne come back after treatment?

Yes, flare-ups can recur, especially if the underlying hormonal or lifestyle factors remain unmanaged. Long-term care helps reduce recurrence.

What happens if cystic acne is left untreated?

It may lead to chronic pain, emotional distress, permanent scarring, and dark pigmentation marks.

Can women develop cystic acne due to PCOS?

Yes. Hormonal imbalances in polycystic ovary syndrome (PCOS) often trigger cystic acne around the jawline, chin, and neck.

How can I prevent cystic acne flare-ups?

Adopt a gentle skincare routine, avoid pore-clogging products, wash your face after sweating, manage stress, and reduce high-glycaemic foods and dairy.

When should I see a doctor for cystic acne?

If you experience painful, persistent, or recurrent acne that leaves scars, consult a specialist for personalised treatment.

References 

  1. Yang, J., Yang, H., Xu, A., & He, L. (2020). A review of advancement on influencing factors of acne: An emphasis on environment characteristics. Frontiers in Public Health, 8, 450. https://doi.org/10.3389/fpubh.2020.00450
  2. Carmina, E., Dreno, B., Lucky, W. A., Agak, W. G., Dokras, A., Kim, J. J., Lobo, R. A., Ramezani Tehrani, F., & Dumesic, D. (2022). Female adult acne and androgen excess: A report from the multidisciplinary androgen excess and pcos committee. Journal of the Endocrine Society, 6(3), bvac003. https://doi.org/10.1210/jendso/bvac003 
  3. ROENGRITTHIDET, K., KAMANAMOOL, N., UDOMPATAIKUL, M., ROJHIRUNSAKOOL, S., KHUNKHET, S., & KANOKRUNGSEE, S. (2021). Association between diet and acne severity: A cross-sectional study in thai adolescents and adults. Acta Dermato-Venereologica, 101(12), 569. https://doi.org/10.2340/actadv.v101.569 
  4. Nodular acne: What it looks like, causes & treatment. (n.d.). Cleveland Clinic. Retrieved August 25, 2025, from https://my.clevelandclinic.org/health/diseases/22888-nodular-acne 
  5. Nodular acne: Symptoms, treatment, scarring, and more. (2017, November 17). Healthline. https://www.healthline.com/health/beauty-skin-care/nodular-acne 
  6. Gallagher, T., Taliercio, M., Nia, J. K., Hashim, P. W., & Zeichner, J. A. (2020). Dermatologist use of intralesional triamcinolone in the treatment of acne. The Journal of Clinical and Aesthetic Dermatology, 13(12), 41–43. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819588/ 
  7. Durairaj, A., Elumalai, K., & Shanmugam, A. (2023). Cystic acne treatment: A comprehensive review. Medicine Advances, 1(4), 318–329. https://doi.org/10.1002/med4.43 
  8. Leyden, J., Stein-Gold, L., & Weiss, J. (2017). Why topical retinoids are mainstay of therapy for acne. Dermatology and Therapy, 7(3), 293–304. https://doi.org/10.1007/s13555-017-0185-2 
  9. Layton, A. (2009). The use of isotretinoin in acne. Dermato-Endocrinology, 1(3), 162–169. https://doi.org/10.4161/derm.1.3.9364 
  10. Bagatin, E., Costa, C. S., Rocha, M. A. D. da, Picosse, F. R., Kamamoto, C. S. L., Pirmez, R., Ianhez, M., & Miot, H. A. (2020). Consensus on the use of oral isotretinoin in dermatology—Brazilian Society of Dermatology. Anais Brasileiros de Dermatologia, 95, 19–38. https://doi.org/10.1016/j.abd.2020.09.001 

About Dr Moses Ng

MBBS (London) with distinction
Dip Practical Dermatology (Cardiff) with distinction
Member of American Acne & Rosacea Society
Fellow of American Society for Laser Medicine & Surgery

Dr. Moses Ng is a distinguished professional in the field of aesthetic medicine, renowned for his expertise in advanced cosmetic procedures. With over 15 years of experience, extensive training and a keen eye for detail, Dr. Ng specializes in a wide range of treatments, including injectables, laser therapies, and acne scar management.

Dr. Moses Ng’s commitment to excellence and patient-centric approach have earned him a reputation as a trusted clinician in aesthetic medicine. His continuous pursuit of the latest advancements in the field ensures that his patients receive the highest standard of care and the most effective treatments available.

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